Cannabidiol (CBD) is gaining popularity across the United States hemp seed oil. Pharmacists must be able to answer patients’ questions about CBD and make recommendations. After reading this article, pharmacists should feel confident about counseling patients about CBD and recommending CBD products. Dr. Martinez also addressed the drug-drug interactions that might occur when CBD is added to other, more traditional therapies. When the enzyme systems in the liver are affected by substances such as CBD, metabolism of other drugs might be sped up or slowed down, affecting the amount of those medications available in the bloodstream.
There’s no denying that CBD, aka cannabidiol, was the reigning trend of last year, and shows no signs of stopping. From edible products and tinctures, to bath and beauty products, CBD was (and is) everywhere. Though touted as a natural, holistic, and safe way to manage a variety of health issues, you may be wondering if you can take CBD and antidepressants together. And while CBD is touted as an all-natural supplement with some evidence that it can be good for your health, it’s possible that your CBD latte can still impact the efficacy of different medications — including antidepressants.
Cannabinoids are a group of compounds that are found in the cannabis sativa plant. There are over 100 cannabinoids found in the hemp plant that are being studied for their potential health benefits. A Doctor’s advice should be sought before using this and any supplemental dietary product. When talking about CBD drug interactions, MedlinePlus says that these can be broken down into two basic categories. Those that could potentially create a dangerous interaction and, therefore, should never be taken with CBD, and those that simply require that you be cautious when combining the two.
While it’s unclear whether CBD oil is effective for weight loss, it has been shown to improve health in other ways. With that said, many benefits of a highly functioning endocannabinoid system are not fully experienced right away. CBD, like all cannabinoids, build up in the body over time and can even stimulate an increase in cannabinoid receptors.
Recent research has shown that CBD interacts with both NSAIDs and opioids through various metabolic pathways, thus allowing less of these drugs for effective pain management. In addition, by activating the CB1 and CB2 neuroreceptors, cannabidiol has pain and inflammation relieving properties of its own that are well documented.
Taking marijuana along with sedative medications might cause too much sleepiness.Some sedative medications include clonazepam (Klonopin), lorazepam (Ativan), phenobarbital (Donnatal), zolpidem (Ambien), and others. Taking marijuana along with sedative medications might cause too much sleepiness. Their use can bring about symptoms of hypertension and tachycardia, the same as stimulant drugs, when combined with Cannabis. Scientific evidence has been suppressed, but anecdotal evidence abounds for the use of Cannabis for various symptoms of mental illness.
“With people taking highly concentrated tinctures and oils containing CBD, I am concerned that there may be some potential interactions with pharmaceuticals,” Abrams says. While there is no specific definition of “highly concentrated,” the doses on the market now are higher than they’ve ever been before. The fact that these concentrates are growing more common, and that some contain higher doses than they advertise, increases the risk. A lack of federal regulation (for now at least) of the CBD space enables such false advertising—and also makes it difficult to know what other substances might be in any given CBD product.
It is also commonly used in conjunction with other medications, so it is important to consider how CBD interacts with other medications. Most notably, the interplay between CBD and cytochrome P450 seems be most prominent when it comes to epilepsy and anti-seizure medications.